路娟,王维宁,赵娟,刘晓秋
LU Juan1,WANG Wei-ning2,ZHAO Juan1,LIU Xiao-qiu1(1.School of Traditional Chinese Materia Medica

• 1:沈阳药科大学中药学院
• 2:辽宁省食品药品检验所

摘要(Abstract)：

目的建立中药酸枣仁的质量评价方法。方法通过测定不同品种和产地酸枣仁药材中黄酮、皂苷、多糖和脂肪油的含量,采用灰关联度法,以定义的相对关联度为测度,构建质量评价模型,并与传统经验鉴别结果相比较。结果对14批样品进行质量排序,优劣情况与经验鉴别结果一致。结论本方法可用于中药酸枣仁的综合性质量评价。
Objective To evaluate systematically the quality of Ziziphi Spinosae Semen.Methods Grey model was set up by determining the contents of flavonoids,saponins,polysaccharides and fat oils contained in the samples,and compared with description identification.Results Fourteen samples were carried out quality orderings,the result showed concordance with description identification.Conclusions Grey incidence degree method and the model can be used to evaluate the quality of Ziziphi Spinosae Semen.

关键词(KeyWords)： 酸枣仁;质量评价;灰关联度法
Ziziphi Spinosae Semen;quality evaluation;grey incidence degree method

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 路娟,王维宁,赵娟,刘晓秋
LU Juan1,WANG Wei-ning2,ZHAO Juan1,LIU Xiao-qiu1(1.School of Traditional Chinese Materia Medica

DOI: 10.14066/j.cnki.cn21-1349/r.2011.07.008

参考文献(References)：

• [1]国家药典委员会.中华人民共和国药典:一部[M].北京:中国医药科技出版社,2010:343-344.
• [2]贺一新,赵素霞,崔瑛.酸枣仁抗焦虑活性物质分析[J].中药材,2010,33(2):229-230.
• [3]CAO Jie-xin,ZHANG Qing-ying,CUI Su-ying,et al.Hypnotic effect of jujubosides from Semen Ziziphi Spi-nosae[J].Journal of Ethnopharmacology,2010,130(1):163-166.
• [4]黄小娟,姜建国,林福兰,等.酸枣仁多糖的提取及其镇静催眠作用的研究[J].现代食品科技,2006,22(2):37-39.
• [5]赵启铎.酸枣仁油中不饱和脂肪酸的药理实验研究[J].天津中医药,2005,22(4):331-333.
• [6]邓聚龙.灰色系统理论教程[M].武汉:华中理工大学出版社,1990:33-84.
• [7]李峰,张振秋,康廷国.灰关联度法评价鹿鞭药材质量研究[J].中药材,2008,31(2):189-192.
• [8]朱诗塔,雷鹏,李新中,等.掌叶大黄不同炮制品指纹图谱与其止血作用的灰关联度分析[J].中南药学,2009,7(1):55-58.
• [9]梁柱华,杨建设,杨艺虹,等.酸枣仁中总黄酮的含量测定研究[J].分析测试技术与仪器,2008,14(1):34-37.
• [10]夏维杰.比色法测定酸枣仁提取物中总皂苷的含量[J].实用药物与临床,2005,8(1):15-16.
• [11]李兰芳,张魁,吴树助,等.酸枣仁中多糖的含量测定[J].河北中医,1996,18(4):20-21.
• [12]ZHANG Ming-chun,ZHANG Yan-qing.Simultaneousdetermination of jujuboside A,B and betulinic acid inSemen Ziziphi Spinosae by high performance liquidchromatography-evaporative light scattering detection[J].Journal of Pharmaceutical and Biomedical Analy-sis,2008,48:1467-1470.
• [13]LIU Jing-jing,CHEN Bo.Simultaneous analysis and i-dentification of main bioactive constituents in extract ofZizyphus jujuba var.sapinosa(Ziziphi spinosae semen)by high-performance liquid chromatography-photodiodearray detection-electrospray mass spectrometry[J].Ta-lanta,2007,71:668-675.
• [14]BAO Kang-de,LI Ping,LI Hui-jun,et al.Simultaneousdetermination of flavonoids and saponins in Semen Ziz-iphi Spinosae(Suanzaoren)by high performance liquidchromatography with evaporative light scattering detec-tion[J].Chinese Journal of Natural Medicines,2009,7(1):47-53.
• [15]陈俊明.酸枣仁及3种伪品的鉴别[J].海峡药学杂志,2005,17(4):401-402.
• [16]杨守鹃.酸枣仁与滇枣仁镇静催眠作用成分-皂苷及黄酮苷含量的比较研究[J].辽宁中医杂志,2006,33(1):105.Quality evaluation of Ziziphi Spinosae Semen by greyincidence degree methodLU Juan1,WANG Wei-ning2,ZHAO Juan1,LIU Xiao-qiu1(1.School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,