珠子参的化学成分Chemical constituents of rhizome of Panacis Majoris
宋小妹,刘越,蔡宝昌
SONG Xiao-mei1,2,LIU Yue1
摘要(Abstract)：
目的对珠子参[PanaxjaponicusC.A.Mey.var.major(Buck.)C.Y.Wu et K.M.Feng]根茎的化学成分进行研究。方法采用硅胶柱色谱进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果分离得到8个化合物,分别鉴定为苯甲酸(benzoin acid,1)、豆甾醇(stigmasterol,2)、齐墩果酸(oleanolic acid,3)、胡萝卜苷(daucosterol,4)、齐墩果酸-28-O-β-D-吡喃葡萄糖苷(oleanolicacid-28-O-β-D-glucopyranoside,5)、齐墩果酸-3-O-β-D-吡喃葡萄糖基(1→2)-β-D-(6′-丁酯)吡喃葡萄糖醛酸苷(oleanolic acid-3-O-β-D-glucopyranoside(1→2)-β-D-glucorunopyranosy-6′-O-butylester,6)、竹节参皂苷IVa(chikusetsusaponinⅣa,7)、人参皂苷Ro(ginsenoside,8)。结论化合物6为新化合物,化合物1、2为首次从该种植物中分离得到。
Objective To study the chemical constituents of Panacis Majoris(the rhizome of [Panax janonicus C.A.Mey.var.major(Buck.)C.Y.Wu et K.M.Feng]).Methods The chemical constituents were isolated by various column chromatographic methods,and the structures of these compounds were identified by MS,1H-NMR and 13C-NMR spectral analysis.Results Eight compounds were isolated and elucidated as:benzoic acid(1),stigmasterol(2),oleanolic acid(3),daucosterol(4),oleanolic acid-28-O-β-D-glucopyranoside(5),oleanolic acid-3-O-β-D-glucopyranoside(1→2)-β-D-glucorunopyranosy-6′-O-butyl ester(6),chikusetsusaponin IVa(7) and ginsenoside Ro(8),respectively.Conclusions Compound 6 is a new compound and compounds 1 and 2 are obtained from this plant for the first time.
关键词(KeyWords)：
珠子参;化学成分;结构鉴定
Panacis Majoris;chemical constituent;structural identification
基金项目(Foundation): 陕西省教育厅2005年科学研究计划项目(05JK168);; 《中华人民共和国药典》2010版一部标准研究(课题编号:YZ-123);; 陕西省科学技术研究发展计划项目[2006K16-G1(2)]
作者(Author):
宋小妹,刘越,蔡宝昌
SONG Xiao-mei1,2,LIU Yue1
DOI: 10.14066/j.cnki.cn21-1349/r.2010.08.010
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