姜春勇;穆淑珍;邓彬;葛永辉;张建新;郝小江;
JIANG Chun-yong2,MU Shu-zhen2,DENG Bin2,GE Yong-hui2,ZHANG Jian-xin2,HAO Xiao-jiang1,2(1.Kunming Institute of Botany,the Chinese Academic of Sciences,State Key Laboratory of Phytochemistry and Plant Resoures in West China,Kunming 650204,China;2.The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences,Guiyang 550002,China)

• 1:贵州省中国科学院天然产物化学重点实验室
• 2:中国科学院昆明植物研究所植物化学与西部植物资源国家重点实验室
• 3:贵州省
• 4:中国科学院天然产物化学重点实验室

摘要(Abstract)：

目的研究水黄花(Euphorbia chrysocomaLévi.et Vant.)地上部分的化学成分。方法运用硅胶柱色谱、RP-18柱色谱、Sephadex LH-20、制备薄层色谱等多种色谱手段和方法分离纯化化合物,采用核磁共振、质谱等现代波谱技术和理化性质鉴定化合物的结构。结果从水黄花地上部分体积分数75%乙醇提取物的乙酸乙酯萃取部位中分离得到6个化合物,分别为没食子酸甲酯(methylgallate,1)、5-羟甲基糠醛(5-hydroxymethyl furaldehyde,2)、大黄酚(chrysophanol,3)、大黄素甲醚(physcion,4)、东莨菪内酯(scopoletin,5)和七叶内酯(aesculetin,6)。结论化合物1⁶均为首次从水黄花中分离得到。
Objective To study the chemical constituents from the aerial part of Euphorbia chrysocoma Lévi. et Vant..Methods All compounds were isolated and purified by many methods,including siliga gel and reversed phase RP-18 column chromatography,preparative thin layer chromatography and Sephadex LH-20.Their structures were mainly elucidated by EI-MS and NMR spectra and their physical characters.Results Six compounds were isolated from the ethyl acetate extract of 75% ethanol of the material.Their structures were identified as methyl gallate(1),5-hydroxymethyl furaldehyde(2),chrysophanol(3),physcion(4),scopoletin(5),aesculetin(6).Conclusions All compounds are isolated from Euphorbia chrysocoma Lévi.et Vant.for the first time.

关键词(KeyWords)： 水黄花;大戟科;大戟属;化学成分;结构鉴定
Euphorbia chrysocoma Lévi. et Vant.;Euphorbiaceae;Euphorbia;chemical constituent;structure identification

Abstract:

Keywords:

基金项目(Foundation): 贵州省优秀科技教育人才省长专项资金项目(黔省专字2008114);; 贵州省科技支撑计划(社会发展攻关)项目(黔科和SY字2009-3105)

作者(Authors): 姜春勇;穆淑珍;邓彬;葛永辉;张建新;郝小江;
JIANG Chun-yong2,MU Shu-zhen2,DENG Bin2,GE Yong-hui2,ZHANG Jian-xin2,HAO Xiao-jiang1,2(1.Kunming Institute of Botany,the Chinese Academic of Sciences,State Key Laboratory of Phytochemistry and Plant Resoures in West China,Kunming 650204,China;2.The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences,Guiyang 550002,China)

DOI: 10.14066/j.cnki.cn21-1349/r.2010.05.004

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