李春梅,王涛,张祎,高秀梅,李天祥
LI Chun-mei1,WANG Tao1,2,ZHANG Yi2,GAO Xiu-mei1

• 1:天津中医药大学中医药研究院
• 2:天津市中药化学与分析重点实验室
• 3:天津中医药大学中药标本馆

摘要(Abstract)：

目的研究中药黄蜀葵(Abelmoschus manihot(L.)Medic.)花的化学成分,为进一步开发利用该植物资源提供依据。方法采用反复硅胶柱色谱、反相ODS、Sephadex LH-20等柱色谱以及高效液相色谱等手段进行分离纯化,并通过理化性质与波谱数据鉴定了化合物的结构。结果分离得到7个以杨梅素为母核的黄酮类化合物,分别鉴定为杨梅素(myricetin,1)、杨梅素-3-O-β-D-葡萄糖苷(myricetin-3-O-β-D-glucopyranoside,2)、cannabiscitrin(3)、杨梅素-3-O-β-D-半乳糖苷(myricetin-O-β-D-galactopyranoside,4)、杨梅素-3-O-芸香糖苷(myricetin-3-O-rutinose,5)、杨梅素-3-O-刺槐糖苷(myricetin-3-O-robinoside,6)、myricetin-3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside(7)。结论化合物4～7为秋葵属植物中首次分离得到。
Objective To continue the study of chemical constituents from the flowers of Abelmoschus manihot(L.)Medic.Methods The compounds were isolated by chromatography such as silica gel,ODS,Sephadex LH-20 and HPLC,and identified by the chemical and physical methods,especially spectral data.Results Seven flavonoids which have myricetin skeleton were isolated.The structures of them were identified as myricetin(1),myricetin-3-O-β-D-glucopyranoside(2),cannabiscitrin(3),myricetin-3-O-β-D-galactopyranoside(4),myricetin-3-O-rutinose(5),myricetin-3-O-robinoside(6)and myricetin-3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside(7),respectively.Conclusion The compounds 47 are obtained from Abelmoschus genus for the first time.

关键词(KeyWords)： 黄蜀葵花;黄酮;杨梅素母核;秋葵属
Abelmoschus manihot(L.)Medic.flos;flavonoid;myricetin skeleton;Abelmoschus species

Abstract:

Keywords:

基金项目(Foundation): 天津市自然科学基金资助项目(09JCYBJC16300);; 科技部“重大新药创制”专项-现代中药新药发现和评价技术平台资助项目(2009ZX09311-002);; 教育部留学回国人员科研启示基金资助项目(教外司留[2010]609号)

作者(Author): 李春梅,王涛,张祎,高秀梅,李天祥
LI Chun-mei1,WANG Tao1,2,ZHANG Yi2,GAO Xiu-mei1

DOI: 10.14066/j.cnki.cn21-1349/r.2010.09.007

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