赵丹丹,李丹毅,魏金霞,华会明,李占林
ZHAO Dan-dan,LI Dan-yi,WEI Jin-xia,HUA Hui-ming,LI Zhan-lin(School of Traditional Chinese Materia Medica

• 1:沈阳药科大学中药学院

摘要(Abstract)：

目的研究文冠果(Xanthoceras sorbifolia Bunge)花的化学成分。方法采用制备薄层色谱、反复硅胶柱色谱、Sephadex LH-20柱色谱、ODS柱色谱等方法进行分离纯化;根据理化性质及光谱数据确定化合物的结构。结果分离得到13个化合物,分别鉴定为对羟基苯甲酸甲酯(methyl 4-hydroxybenzoate,1)、白桦脂醇(betulin,2)、山柰酚(kaempferol,3)、槲皮素(quercetin,4)、槲皮苷(quercitrin,5)、东莨菪素(scopoletin,6)、鼠李柠檬素(rhamnocitrin,7)、芦丁(rutin,8)、异杨梅树皮苷(myricetin-3-O-β-D-glucopyranoside,9)、1-O-甲基-肌-肌醇(1-O-methyl-myo-inositol,10)、柚皮素(naringenin,11)、柯依利素(chrysoeriol,12)、山柰酚-3-O-(2-O-α-L-鼠李糖基)-β-D-葡萄糖苷(kaempferol-3-O-(2-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside,13)。结论化合物1、7、9、12-13为首次从文冠果属植物中分离得到。
Objective To study the chemical constituents of the flower of Xanthoceras sorbifolia Bunge.Methods The constituents were isolated and purified by preparative TLC and silica gel,Sephadex LH-20,and ODS column chromatography,and their chemical structures were elucidated by their physico-chemical properties and spectral analysis.Results Thirteen compounds were obtained and identified as methyl 4-hydroxybenzoate(1),betulin(2),kaempferol(3),quercetin(4),quercitrin(5),scopoletin(6),rhamnocitrin(7),rutin(8),myricetin-3-O-β-D-glucopyranoside(9),1-O-methyl-myo-inositol(10),naringenin(11),chrysoeriol(12),kaempferol-3-O-(2-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside(13).Conclusions Compounds 1,7,9,12-13 are isolated from Xanthoceras genus for the first time.

关键词(KeyWords)： 文冠果;花;化学成分;结构鉴定;黄酮
Xanthoceras sorbifolia;flower;chemical constituent;structural elucidation;flavonoid

Abstract:

Keywords:

基金项目(Foundation): 辽宁省博士启动基金(20081037)

作者(Author): 赵丹丹,李丹毅,魏金霞,华会明,李占林
ZHAO Dan-dan,LI Dan-yi,WEI Jin-xia,HUA Hui-ming,LI Zhan-lin(School of Traditional Chinese Materia Medica

DOI: 10.14066/j.cnki.cn21-1349/r.2012.07.002

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