刺乌养心口服液的高效液相色谱指纹图谱研究Study on HPLC fingerprint of Ciwu Yangxin oral liquid
王威,李敬伟,赵旻,王淼,赵春杰
WANG Wei,LI Jingwei,ZHAO Min,WANG Miao,ZHAO Chunjie
摘要(Abstract):
目的 研究不同批次中药制剂刺乌养心口服液的指纹图谱。方法 采用HPLC法,以丹参素钠为参照物对10批刺乌养心口服液进行分析,并评价10批样品指纹图谱的相似度。结果 在刺乌养心口服液指纹图谱中有20个共有峰,指认其中6个,相似度值为0.986~0.997。结论 所建立的指纹图谱可为刺乌养心口服液的质量控制提供科学的参考。
Objective To study the fingerprints of different batches of traditional Chinese medicine preparation Ciwu Yangxin Oral Liquid.Methods Analyze 10 batches of Ciwu Yangxin liquid by HPLC with Danshensu sodium as the reference substance, and evaluate the similarity of the fingerprints of the 10 batches of samples obtained.Results There are 20 shared chromatographic peaks in the fingerprint spectrum of Ciwu Yangxin oral liquid, and 6 of them are identified, with similarity values ranging from 0.986 to 0.997.Conclusion The established fingerprint has good repeatability and stability, which can provide a scientific reference for the quality control of Ciwu Yangxin oral liquid.
关键词(KeyWords):
刺乌养心口服液;高效液相色谱;指纹图谱
Ciwu Yangxin oral liquid;high performance liquid chromatography;fingerprint
基金项目(Foundation):
作者(Author):
王威,李敬伟,赵旻,王淼,赵春杰
WANG Wei,LI Jingwei,ZHAO Min,WANG Miao,ZHAO Chunjie
DOI: 10.14066/j.cnki.cn21-1349/r.2021.0017
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