吕帅,许磊,黄健,高慧媛,吴立军
LShuai,XU Lei,HUANG Jian,GAO Hui-yuan,WU Li-jun(School of Traditional Chinese Materia Medica

• 1:沈阳药科大学中药学院

摘要(Abstract)：

目的对辽细辛地下部分进行化学成分研究。方法采用反复硅胶色谱法分离纯化,通过理化性质和NMR谱学数据鉴定其化学结构。结果从辽细辛地下部分分离得到7个化合物,分别鉴定为卡枯醇(kakuol,1)、2-甲氧基-4,5-亚甲二氧基苯丙酮(2-methoxy-4,5-methylene-dioxypropi-ophenone,2)、(-)-芝麻脂素((-)-sesamin,3)、(-)-细辛脂素((-)-asarinin,4)、pluviatilol(5)、5-羟甲基糠醛(5-hydroxymethylfurfural,6)、正丁基-吡喃果糖苷(n-butylfructopyranoside,7)。结论化合物6、7为首次从细辛属中分离得到,化合物2、5为首次从该植物中分离得到。
Objective To study the chemical constituents of the root of Asarum heterotropides Fr Schmidt.var.mandshuricum(Maxim.)Kitag.Methods The compounds were isolated by chromatography on silica gel column and identified on the physico-chemical properties and spectral analysis.Results Seven compounds were obtained and identified as kakuol(1),2-methoxy-4,5-methylene-dioxypropiophenone(2),(-)-sesamin(3),(-)-asarinin(4),pluviatilol(5),5-hydroxymethylfurfural(6),n-butylfructopyranoside(7).Conclusions Compounds 6 and 7 are firstly isolated from Asarum.Compounds 2 and 5 are isolated from Asarum heterotropides Fr Schmidt.var.mandshuricum(Maxim.)Kitag.for the first time.

关键词(KeyWords)： 辽细辛;化学成分;地下部分;结构鉴定
Asarum heterotropides Fr Schmidt.var.mandshuricum(Maxim.)Kitag.;undergrand part;chemical constituent;structure identification

Abstract:

Keywords:

基金项目(Foundation): 国家科技支撑计划子课题(2006BAI06A00)

作者(Author): 吕帅,许磊,黄健,高慧媛,吴立军
LShuai,XU Lei,HUANG Jian,GAO Hui-yuan,WU Li-jun(School of Traditional Chinese Materia Medica

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