丹皮酚兔体内吸收试验THE ABSORPTION EXPERIMENT OF PAEONOL IN RABBIT
戴玉英,胡晋
Dai Yuying Liuzhou Pharmaceutical Factory,Guangxi Hu Jin Shenyang College of Pharmacy
摘要(Abstract)：
牡丹皮中主要成分丹皮酚通过兔口服,作了吸收试验。取其尿液经薄层层析分离,再用双波长色谱扫描法测定其代谢产物,证明丹皮酚口服后能被吸收,并从排出物尿中检出丹皮酚、2,4-二羟基乙酰苯和2,5-二羟基-4-甲氧基乙酰苯三种物质,为研究丹皮酚口服给药提供了实验依据。
The absorption tests of paeonol which was taken orally by rabbits were reported.The fact that the resulting material from the isolation of urine and three metabolites could be absorbed orally by rabbits was demonstrated by using dual wavelength thin layer chromatography method.
关键词(KeyWords)：
丹皮酚;2,5-二羟基-4-甲氧基乙酰苯;2,4-二羟基乙酰苯;生物利用度
paeonol;2,5-Dihydroxy-4-methoxy acetyl benzene;2,4-Hydroxy acetyl benzene;Bioavailability
基金项目(Foundation):
作者(Author):
戴玉英,胡晋
Dai Yuying Liuzhou Pharmaceutical Factory,Guangxi Hu Jin Shenyang College of Pharmacy
- 丹皮酚
- 2,5-二羟基-4-甲氧基乙酰苯
- 2,4-二羟基乙酰苯
- 生物利用度
paeonol - 2,5-Dihydroxy-4-methoxy acetyl benzene
- 2,4-Hydroxy acetyl benzene
- Bioavailability