王陶陶,董宇,常生,殷军
WANG Taotao,DONG Yu,CHANG Sheng,YIN Jun

• 1:沈阳药科大学中药学院
• 2:辽宁省药品检验检测院

摘要(Abstract)：

目的综述朱砂对神经系统、肝肾和生殖系统毒性的特点、作用机制及应对措施。方法查阅国内外近年来相关文献,对其进行归纳、总结。从朱砂的基础概述,毒性的研究概况、作用机制及应对策略进行介绍。结果朱砂虽会引起毒性,但在镇静安神等中医药领域发挥着重要作用。只要合理应用、规避毒性就可以更好地发挥其药效。结论作者概述了朱砂毒性的研究进展,旨在进一步了解朱砂毒性,减少或避免在中医药临床应用中的毒副反应,为朱砂的临床合理应用提供科学依据,并为科学的认识朱砂的毒性提供参考。
Objective To reviewthe characteristics,mechanisms and counter-measures of cinnabar toxicity to the nervous system,liver and kidney,and the reproductive system,provides help for further application of cinnabar. Methods The relevant literature published in China and abroad the recent years were consulted and summarized. The introduction of cinnabar and the characteristics,mechanisms and counter-measures of cinnabar toxicity were reviewed. Results Although cinnabar could cause toxicity,it as a sedative and a soporific plays an important role in the field of Chinese medicine. The toxicity of cinnabar could be avoided at the basic of using it rationally,which will contribute to exerting better efficacy. Conclusion The authors outlined the research progress on toxicity in order to further understand the toxicity of cinnabar,to reduce or avoid toxic and side effects in TCM clinic,which could provide the scientific basis for the clinical rational application of cinnabar and provide scientific reference for the toxicity of cinnabar.

关键词(KeyWords)： 朱砂;汞;毒性;机制
cinnabar;mercury;toxicity;mechanism

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(81573628)

作者(Author): 王陶陶,董宇,常生,殷军
WANG Taotao,DONG Yu,CHANG Sheng,YIN Jun

DOI: 10.14066/j.cnki.cn21-1349/r.2018.10.015

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