马志强,宋少江,陈广通,杨玉建,徐绥绪
MA Zhi-qiang; SONG Shao-jiang; CHEN Guang-tong; YANG Yu-jian; XU Sui-xu (School of Traditional Chinese Materia Medica;

• 1:沈阳药科大学中药学院
• 2:沈阳药科大学中药学院
• 3:沈阳药科大学中药学院
• 4:沈阳药科大学中药学院

摘要(Abstract)：

目的分离、鉴定辽东木 (Araliaelata(Miq )Seem )芽提取物 (总皂苷 )中的化学成分。方法利用硅胶柱色谱 ,制备高效液相柱色谱进行分离纯化 ,根据理化性质和光谱数据进行结构鉴定。结果得到 5个化合物 ,分别鉴定为congmuyenosideA(1) ,congmuyenosideB(2 ) ,木皂苷Ⅶ(congmunosideⅦ ,3) ,3 O β D glucopyranosyl (1→ 3) α L arabinopyranosylechinocysticacid(4) ,腺苷 (adenosine,5 )。结论化合物 4和 5为首次从该属植物中分离。
Objective To study the chemical constituents of the extract (crude saponins) of the buds of Aralia elata (Miq.) Seem.Methods The chemical constituents were isolated by silica gel column chromatography and preparative HPLC,physical-chemical characters and the spectroscopic analysis were employed for the structural identification. Results Compound 1～5 were obtained and their structures were elucidated as congmuyenoside A (2),congmuyenoside B (2),congmunoside Ⅶ (3),3-O-β-D-glucopyranosyl (1→3)-α-L-arabinopyranosyl echinocystic acid (4),adenosine (5).Conclusions Compound 4 and 5 are isolated from Aralia elata for the first time.

关键词(KeyWords)： 结构鉴定;核磁共振波谱;辽东楤木;三萜皂苷
structure identification; NMR; Aralia elata; triterpenoidal saponin

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 马志强,宋少江,陈广通,杨玉建,徐绥绪
MA Zhi-qiang; SONG Shao-jiang; CHEN Guang-tong; YANG Yu-jian; XU Sui-xu (School of Traditional Chinese Materia Medica;

参考文献(References)：

• [1]王忠壮,胡晋红,于占洋,等.木属植物的生物学研究及应用[M ].上海:第二军医大学出版社,2001.4-7.
• [2]KuangHS ,SunH ,ZhangN ,etal.Twonewsaponins,congmuyenosidesAandB ,fromtheleavesofAraliae latacollectedinheilongjiang,china[J].ChemPharmBull,1996,44(11):2183-2185.
• [3]SongSJ ,NakamulaN ,MaCM ,etal.FivenewsaponinsfromtherootbarkofAraliaelata[J].Phytochemistry,2001,56:491-497.
• [4]StrigunovVS ,GrishkovetsVI ,ShashkovAS ,etal.Triterpene glycosidesfromTetrapanaxpapyriferum.Ⅲ.Minormonodesmosideglycosidesfromstembark[J].ChemNatCompd,2001,37(5):462-465.
• [5]ChenonMT ,PugmireRJ ,GrantDM ,etal.Abasicsetofparametersfortheinvestigationoftautomerisminpurinesestablishedfromcarbon13magneticresonancestudiesusingcertainpurinesandpyrrolo[2,3 d]pyrim idines[J].JAmChemSoc,1975,97:4627.