白眉短尾蝮蛇青精氨酸酯酶组分的药理研究 (一)血液流变学方面作用PHARMACOLOGICAL STUDIES ON ARGININE ESTERASE FRACTIONS OF AGKISTRODON H BREVICAUDUS STEJNEGER VENOM 1. Effects on Hemorheology
王世久;张世轩;刘大伟;薛淑英;韩中秀;耿义;
Wang Shijiu Zhang Shixuan Liu Dawei Han Zhongxiu Xue Shuying Geng Yi Shenyang College of Pharmacy
摘要(Abstract)：
白眉短尾蝮蛇(Agkistrodon h Brevicaudus Stejneger)毒的精氨酸酯酶组分以0.024u～0.4u/kg剂量给药,使家兔、狗的血浆纤维蛋白原、血脂、红细胞压积、全血比粘度、血浆比粘度均降低。从整体及试管实验证明能改变家兔、狗的血液流变学等几项指标。
Arginine esterase of Agkistrodon h Brevicaudus Stejneger Venom is injected intravenously by 0.024-0.4u/kg to induce decrease of fibrinogenopenia,blood fat as well as hematocrit viscosity ratio of blood and plasma in rabbits and dogs.It is proved that the arginine esterase is able to change some indices of hemorheology in rabbits and dogs.
关键词(KeyWords)：
精氨酸酯酶;血液流变学;白眉短尾蝮蛇毒
Arginine esterase; Hemorheology; Agkistrodon h Brevicaudus stejneger Venom
基金项目(Foundation):
作者(Authors):
王世久;张世轩;刘大伟;薛淑英;韩中秀;耿义;
Wang Shijiu Zhang Shixuan Liu Dawei Han Zhongxiu Xue Shuying Geng Yi Shenyang College of Pharmacy
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