张向荣,潘卫三
ZHANG Xiang rong; PAN Wei san (School of Pharmacy ;

• 1:沈阳药科大学药学院
• 2:沈阳药科大学药学院 辽宁沈阳110016
• 3:辽宁沈阳110016

摘要(Abstract)：

目的研究丹参酚酸A在大鼠小肠的吸收情况。方法采用大鼠在体小肠回流实验装置 ,利用UV双波长法测定肠循环液中酚红和丹参酚酸A含量。结果表明丹参酚酸A在大鼠小肠的平均吸收率为 2 0 5 %。结论在低、中、高 3种不同浓度下 ,吸收速率常数无显著差异 ,其吸收机制为被动扩散。
Objective Intestinal absorption experiments of rats in vivo were used to study the absorption of salvianoic acid A. Method A method was developed for the determination of salvianoid acid A and phenol red in intestinal solution by UV. Result The average absorption of salvianoic acid A in rat′s small intestines in vivo was 20 5%.Conclusion The absorption kinetics experiments showed that there were no marked difference between K a at these concentrations. The transport mechanism of salvianoic acid A was passive diffusion.

关键词(KeyWords)： 丹参酚酸A;吸收动力学;紫外分光光度法
salvianoic acid A; small intestinal absorption kinetics; UV

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 张向荣,潘卫三
ZHANG Xiang rong; PAN Wei san (School of Pharmacy ;

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