莫索尼定的电离常数和分配系数的测定The determination of the ionization constant and partition coefficient of moxonidine
张远杏,武凤兰,李玉珍
ZHANG Yuan xing 1; WU Feng lan 2; LI Yu zhen 1 (1 Department of Pharmacy;
摘要(Abstract)：
在 2 5℃下 ,分别测定了莫索尼定的电离常数和分配系数。采用电位滴定法测得莫索尼定的电离常数 pKTa 值为 7 35± 0 0 3。采用摇瓶法测得莫索尼定的分配系数为P =12 0 2± 0 13
The methods were described for determining the ionization constant and partition coefficient of moxonidine. The ionization constant was determined by the potential titration method,and the p K T a was 7 35±0 03.The partition coefficient was determined by the bottle shaking method,and the P = 12 02±0 13 .
关键词(KeyWords)：
莫索尼定;电离常数;分配系数
moxonidine; ionization constant; partition coefficien
基金项目(Foundation):
作者(Authors):
张远杏,武凤兰,李玉珍
ZHANG Yuan xing 1; WU Feng lan 2; LI Yu zhen 1 (1 Department of Pharmacy;
参考文献(References)：
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