一氧化氮供体与心血管病治疗药Nitric oxide donors and cardiovascular medicines
戴厚玲,陈玉彬
DAI Hou-ling; CHEN Yu-bin (School of Pharmaceutical Engineering;
摘要(Abstract):
目的介绍一氧化氮供体药物的研究进展。方法根据相关文献 ,进行分析整理和归纳。结果与结论为一氧化氮供体药物的研究和开发提供了参考
Objective To focus attention on nitric oxide donor drugs.Methods A number of literature involved was analysed,rearranged and summed up.Results and Conclusions The review provides a reference to the research and development of nitric oxide donor drugs.
关键词(KeyWords):
一氧化氮;一氧化氮合成酶;一氧化氮供体
nitric oxide; nitric oxide synthases; nitric oxide donor
基金项目(Foundation):
作者(Authors):
戴厚玲,陈玉彬
DAI Hou-ling; CHEN Yu-bin (School of Pharmaceutical Engineering;
参考文献(References):
- [1]丁刚.心肌缺血再灌注时一氧化氮与心功能的关系[J].心血管病学进展,1999,20(5):287-289.
- [2]WitoldK ,MariuszZ ,AlbertWG .Nitricoxideinhibi tionoffreeradical mediatedcholesteralperoxidationinliposomalmembranes[J].Biochemistry,2000,39(23):6918-6928.
- [3]郭国庆,查彩慧.一氧化氮和动脉粥样硬化的关系[J].心血管病学进展,2001,22(3):178-180.
- [4]AllanML ,DavidJL .Therapeuticroleofnitricoxidedonorsinthetreatmentofcardiovasculardisease[J].DrugsoftheFuture,1994,19(7):665-672.
- [5]顾振纶,卞春甫,张银娣,等.医学药理学[M ].北京:科学出版社,1999.203-206.
- [6]CeredaR ,BertoliniG ,GromoG ,etal.Sinitrodi[J].DrugsoftheFuture,1997,22(3):242-248.
- [7]HelmutB ,KarlS .Oxygenandoxidationpromotethereleaseofnitricoxidefromsydnonimines[J].JournalofCardiovascularPharmacology,1989,14(suppl.11):S6-S12.
- [8]MingX ,KunW ,ChenXC ,etal.Inhibitionofproteintyrosinephosphatasesbylowmoleuclar weightS ni trosothiolsandS nitrosylatedhumanserumalbumin[J].BiochemicalandBiophysicalResearchCommuni cations,2000,268(2):310-314.
- [9]MichaelEM .Influenceofredoxcompoundsonnitrova sodilator inducedrelaxationsofratcoronaryarteries[J].BritishJournalofPharmacology,1999,128(2):435-443.
- [10]ChrisMM ,DeborahM ,DavidAW ,etal.ComplexesofNOwithnucleophilesasagentsforthecontrolledbio logicalreleaseofnitricoxidevasorelaxanteffects[J].JournalofMedicinalChemistry,1991,34(11):3242-3247.
- [11]ToyakazuI,NatsukiS ,YasushiK ,etal.EffectofFK409,anovelnitricoxidedonor,onacuteexperimen talmyocardialischemia[J].TheJapaneseJournalofPharmacology,1993,62(3):315-324.
- [12]JohjiF ,StefanoS ,IvanT ,etal.FK409,aspontaneousnitricoxidereleaser,attenuatesallograftvasculopathyinarataortictransplantmodel[J].CirculationRe search,2000,87(1):66-72.
- [13]张美珍.BiDil已获美国可批准信件[J].国外药讯,2001,7:12.