韩凌飞,耿剑亮,孟大利,李宁,李铣
HAN Ling-fei,GENG Jian-liang,MENG Da-li,LI Ning,LI Xian(School of Traditional Chinese Materia Medica

• 1:沈阳药科大学中药学院

摘要(Abstract)：

目的研究东革阿里的化学成分。方法采用反复硅胶柱色谱法、Sephadex LH-20柱色谱法和重结晶等进行分离纯化,并通过波谱分析技术鉴定其化学结构。结果从东革阿里中分离得到5个化合物,分别鉴定为:东莨菪素(scopoletin,1)、9-甲氧基-铁屎米-6-酮(9-methoxycanthin-6-one,2)、3-(7-甲氧基-β-咔巴啉-1)-丙酸(7-methoxy-β-carbolin-1-propionic acid,3)、laurycolactone A(4)、3-(7-甲氧基-β-咔巴啉-1)-丙酸甲酯(7-methoxyinfractin,5)。结论化合物1-4为已知化合物,化合物5为新化合物。
Objective To study the chemical constituents of Eurycoma longifolia Jack.Methods The compounds were isolated by chromatography on silica gel column,Sephadex LH-20 column and recrystallization methods,and their structures were determined on the basis of special analysis.Results Five compounds were obtained and identified as scopoletin(1),9-methoxycanthin-6-one(2),7-methoxy-β-carbolin-1-propionic acid(3),laurycolactone A(4),7-methoxyinfractin(5).Conclusions Compounds 1-4 are four known compounds and compound 5 is a new compound.

关键词(KeyWords)： 东革阿里;化学成分;结构鉴定;7-methoxyinfractin
Eurycoma longifolia Jack;chemical constituent;structural identification;7-methoxyinfractin

Abstract:

Keywords:

基金项目(Foundation): 辽宁省“百千万人才工程”资助项目(2010921074)

作者(Author): 韩凌飞,耿剑亮,孟大利,李宁,李铣
HAN Ling-fei,GENG Jian-liang,MENG Da-li,LI Ning,LI Xian(School of Traditional Chinese Materia Medica

DOI: 10.14066/j.cnki.cn21-1349/r.2011.07.005

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