苦碟子化学成分的分离与鉴定Isolation and identification of the constituents from whole plant of Ixeris sonchifolia(Bge.)Hance
侯晶,艾瑞婷,周凌艳,刘冰洁,李玲芝,彭缨
HOU Jing1,AI Rui-ting2,ZHOU Ling-yan1,LIU Bing-jie1,LI Ling-zhi1,PENG Ying1(1.School of Pharmacy
摘要(Abstract)：
目的对菊科苦荬菜属植物抱茎苦荬菜[Ixeris sonchifolia(Bge.)Hance]的化学成分进行研究。方法运用硅胶﹑聚酰胺柱色谱﹑Sephadex LH-20柱色谱﹑ODS柱色谱、制备HPLC等分离手段进行化学成分的分离纯化,根据理化性质及波谱数据鉴定其结构。结果从苦碟子全草中分离得到4个化合物。分别鉴定为3β-hydroxyolean-12-en-11-one acetate(1)、3,4-dihydroxybenzalacetone(2)、7-O-β-D-glucopyranosyl-luteolin-3'-O-β-D-glucopyranoside(3)、5,7-dihydroxy-4'-methoxy-fla-vone-7-rutinoside(4)。结论这些化合物均为首次从该属植物中分离得到。
Objective To study the chemical constituents of the whole plant of Ixeris sonchifolia(Bge.)Hance. Methods Four compounds were isolated by chromatographies on silica gel column,polyamide,Sephadex LH-20,ODS column,PHPLC and identified on the basis of physico-chemical constant and spectroscopic analysis. Results Four compounds were separated from the extract of Ixeris sonchifolia.On the basis of chemical and spectral methods.These compounds were elucidated as 3β-hydroxyolean-12-en-11-one acetate( 1),3,4-dihydroxybenzalacetone( 2),7-O-β-D-glucopyranosyl-luteolin-3′-O-β-D-glucopyranoside( 3),5,7-dihydroxy-4′-methoxyflavone-7-rutinoside( 4). Conclusions All these compounds were isolated from this genus for the first time
关键词(KeyWords)：
抱茎苦荬菜;化学成分;结构鉴定
Ixeris sonchifolia(Bge.)Hance;chemical constituent;structural identification
基金项目(Foundation):
作者(Author):
侯晶,艾瑞婷,周凌艳,刘冰洁,李玲芝,彭缨
HOU Jing1,AI Rui-ting2,ZHOU Ling-yan1,LIU Bing-jie1,LI Ling-zhi1,PENG Ying1(1.School of Pharmacy
DOI: 10.14066/j.cnki.cn21-1349/r.2011.11.005
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