沈阳药科大学学报

2001, (05) 329-331

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噻二嗪硫酮类抑菌衍生物的合成
Synthesis of antimicrobial derivatives of thiadiazinethiones

张枫,陈改清,邹静恂
ZHANG Feng; CHEN Gai qing; ZOU Jing xun (Department of Chemistry;

摘要(Abstract):

通过用相应的脂肪胺与氢氧化钾、二硫化碳反应 ,然后加入甲醛和对氨基苯甲酸 ,共合成了5个新的 1 ,3 ,5 噻二嗪 2 硫酮类抑菌化合物 ,并对这 5个化合物进行了元素分析和紫外、红外、氢核磁的谱图分析 ,且与结构相符
Five new antimicrobial derivatives of 1,3,5 thiadiazine 2 thione were synthesized by the reaction of appropriate alkyl amine with potassium hydroxide and carbon disulfide,followed by formaldehyde and p aminobenzoic acid. The structures of these compounds had been confirmed by elementary analysis, UV, IR and 1H NMR .

关键词(KeyWords): 噻二嗪硫酮类化合物;抑菌化合物;合成
thiadiazinethiones; antimicrobial compound; synthesis

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 张枫,陈改清,邹静恂
ZHANG Feng; CHEN Gai qing; ZOU Jing xun (Department of Chemistry;

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