金秀梅,吴迪,黄健,孙博航,吴立军,高慧媛
JIN Xiu-mei1,WU Di2,HUANG Jian1,SUN Bo-hang1,WU Li-jun1,GAO Hui-yuan1 (1.School of Traditional Chinese Materia Medica

• 1:沈阳药科大学中药学院
• 2:辽宁省公安厅刑科所

摘要(Abstract)：

目的对板栗总苞(Castanea mollissimaBlume)的化学成分进行深入研究。方法采用硅胶柱色谱、凝胶柱色谱和制备性HPLC等多种分离方法对板栗总苞体积分数为95%乙醇溶液回流提取物进行成分分离,结合化合物的理化常数、谱学分析等方法鉴定其结构。结果分离得到10个化合物,分别鉴定为8-(3,5-dihydroxyphenyl)-1-propyloctyl 2,4-dihydroxy-6-undecylbenzoate(1)、苹果酸二丁酯(dibutylmalate,2)、槲皮素(quercetin,3)、山柰酚(kaempferol,4)、tiliroside(5)、山柰酚3-O-(2″,6″-双-反式-对-香豆酰基)-β-D-吡喃葡萄糖苷(kaempferol-3-O-[2″,6″-di-O-(E)-p-coumaroyl]β-D-glucopyranoside,6)、3′,3″-dimethoxylarreatricin(7)、大黄素(emodin,8)、乌索酸(ursolic acid,9)、原儿茶酸(3,4-dihydroxybenzoic acid,10)。结论化合物1、2为从栗属植物中首次分离得到,化合物8为该种植物中首次分离得到,以上化合物均为板栗总苞中首次分离得到。
Objective To isolate the chemical constituents and elucidate their structures from the involucres of Castanea mollissima Blume.Methods Compounds were isolated by column chromatography on silica gel columns,Sephadex LH-20 and preparative HPLC methods.Physical-chemical properties and spectral analysis were employed for the structural elucidation.Results Ten compounds were obtained and identified as 8-(3,5-dihydroxyphenyl)-1-propyloctyl 2,4-dihydroxy-6-undecylbenzoate(1),dibutylmalate(2),quercetin(3),kaempferol(4),tiliroside(5),kaempferol-3-O-[2″,6″-di-O-(E)-p-coumaroyl]-glucopyranoside(6),3′,3″-dimethoxylarreatricin(7),emodin(8),ursolic acid(9),3,4-dihydroxybenzoic acid(10),respectively.Conclusions Compounds 1 and 2 are isolated from this genus for the first time,and compound 8 is isolated from this plant for the first time,while,all compounds are reported for the involucre part firstly.

关键词(KeyWords)： 板栗总苞;化学成分;结构鉴定
Castanea mollissima Blume;chemical constituent;structural identification

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 金秀梅,吴迪,黄健,孙博航,吴立军,高慧媛
JIN Xiu-mei1,WU Di2,HUANG Jian1,SUN Bo-hang1,WU Li-jun1,GAO Hui-yuan1 (1.School of Traditional Chinese Materia Medica

DOI: 10.14066/j.cnki.cn21-1349/r.2010.08.005

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