张怡轩,陈晓莹,赵文倩
ZHANG Yi-xuan,CHEN Xiao-ying,ZHAO Wen-qian(School of Life Science and Biopharmaceutics

• 1:沈阳药科大学生命科学与生物制药学院
• 2:沈阳药科大学生命科学与生物制药学院
• 3:沈阳药科大学生命科学与生物制药学院 辽宁沈阳110016
• 4:辽宁沈阳110016

摘要(Abstract)：

目的综述人参皂苷在体内及体外的生物转化研究概况。方法查阅国内外相关文献,以其中的26篇文献为依据对人参皂苷在体内的转化途径及产物加以介绍,也对体外转化中使用的酶法和微生物法加以详细阐述。结果人参皂苷在体内被代谢成为多种稀有人参皂苷,它们是人参在体内发挥药理活性作用的物质。体外生物转化人参皂苷的方法较多,并取得了许多有意义的成果。结论为人参皂苷的代谢研究及稀有人参皂苷的体外生物转化制备提供了参考。
Objective To summarizes the general situation of nature ginsenoside biotransformation in vivo and in vitro.Methods Domestic and international references were comprehensively reviewed;a detailed introduction about nature ginsenosides metabolites and pathways were expatiated when in vivo or biotransformed by enzymatic hydrolysis or microorganism.Results In human body,nature ginsenosides were transformed into rare ginsenosides which are the really pharmacological components.Many significant achievements had been reported on ginsenosides biotransformation in vitro.Conclusions This article will provide references for the metabolism study of ginsenosides and the biological preparation of rare ginsenosides.

关键词(KeyWords)： 人参皂苷;生物转化;微生物;酶解法
ginsenosides;biotransformation;microorganism;enzymatic hydrolysis

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 张怡轩,陈晓莹,赵文倩
ZHANG Yi-xuan,CHEN Xiao-ying,ZHAO Wen-qian(School of Life Science and Biopharmaceutics

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