促肝细胞生长素冻干脂质体的制备与物理化学性质研究Studies on preparation and physico-chemico properties of freeze-drying liposome of promoting hepatocyte growth factor (PHGF)
赵海英,王思玲,苏德森
ZHAO Hai ying; WANG Si ling; SU De sen (School of Pharmacy;
摘要(Abstract)：
优化处方工艺 ,制备了促肝细胞生长素冻干脂质体。考察其再分散后的性质包括透射电镜观察形态、粒度分布、电学性质、物理稳定性和流变性 ,同时进行了化学稳定性考察 ,预测促肝细胞生长素冻干脂质体在 4～ 8℃下的t0 9为 5 5 6d。
The freeze drying liposome of promoting hepatocyte growth factor (PHGF) was optimized; properties of liposome suspension such as form, size distribution, electrology, physical stability and rheology were studied; results of the chemical stability indicated t 0 9 of PHGF freeze drying liposome was 556 days.
关键词(KeyWords)：
促肝细胞生长素;冻干脂质体;化学稳定性
promoting hepatocyte growth factor; freeze drying liposome; chemical stability
基金项目(Foundation):
作者(Authors):
赵海英,王思玲,苏德森
ZHAO Hai ying; WANG Si ling; SU De sen (School of Pharmacy;
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