艾叶的化学成分(Ⅱ)Chemical constituents from the Folium Artemisiae Argyi(Ⅱ)
吉双,卢桂荣,孟大利,李宁,李铣
JI Shuang1,LU Gui-rong2,MENG Da-li1,LI Ning1,LI Xian1(1.School of Traditional Chinese Materia Medica
摘要(Abstract)：
目的对中药艾叶(Folium Artemisiae Argyi)的化学成分进行分离鉴定。方法采用反复硅胶柱色谱、Sephadex LH-20凝胶柱色谱、制备TLC、重结晶等方法进行分离纯化,通过理化常数测定和波谱分析等手段鉴定其化学结构。结果分离得到10个化合物,分别鉴定为isotanciloide(1)、伞形花内酯(umbelliferone,2)、瑞香素(daphnetin,3)、圣草酚(eriodictyol,4)、鼠李素(rhamnetin,5)、高车前素(hispidulin,6)、L-2-O-甲基-手-肌醇(L-2-O-methyl-chiro-inositol,7)、豆甾醇(stigmasterol,8)、胡萝卜苷(daucosterol,9)、4-甲氧基-3-羟基苯酚(4-methoxyl-3-hydroxyphenol,10)。结论其中,化合物10为新天然产物,化合物1-5、7为首次从艾叶中分离得到。
Objective To isolate the constituents of Folium Artemisiae Argyi and identify their structures.Methods The compounds were isolated by chromatography on silica gel column,Sephadex LH-20,preparative TLC and recryztallization,and identified on the basis of physico-chemical constants and spectral analysis.Results Ten compounds were identified as isotanciloide(1),umbelliferone(2),daphnetin(3),eriodictyol(4),rhamnetin(5),hispidulin(6),L-2-O-methyl-chiro-inositol(7),stigmasterol(8),daucosterol(9)and 4-methoxyl-3-hydroxyphenol(10).Conclusions Compound 10 is a newly discovered natural product,and compounds 15 and 7 are firstly isolated from Folium Artemisiae Argyi.
关键词(KeyWords)：
艾叶;化学成分;结构鉴定
Folium Artemisiae Argyi;chemical constituent;structure identification
基金项目(Foundation):
作者(Author):
吉双,卢桂荣,孟大利,李宁,李铣
JI Shuang1,LU Gui-rong2,MENG Da-li1,LI Ning1,LI Xian1(1.School of Traditional Chinese Materia Medica
DOI: 10.14066/j.cnki.cn21-1349/r.2010.07.005
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